- Transdermal drug
delivery provides excellent control of the rate of delivery directly
into the bloodstream. It also offers a predictable pharmacokinetic
profile and constant drug levels over extended periods of time without
the extreme peak/trough fluctuations inherent in oral administration.
And discontinuation of therapy can be achieved immediately by simply
removing the patch.
- Pharmaceutical-grade films, backings, Adhesives and liners for
use in manufacturing transdermal drug delivery systems.
- Throughout the
past 2 decades, the transdermal patch has become a proven technology
that offers a variety of significant clinical benefits over other dosage
forms. Because transdermal drug delivery offers controlled release of
the drug into the patient, it enables a steady blood-level profile,
resulting in reduced systemic side effects and, sometimes, improved
efficacy over other dosage forms.In addition, because transdermal
patches are user-friendly, convenient, painless, and offer multi-day
dosing, it is generally accepted that they offer improved patient
- The introduction
of transdermal gel technology in the U.S. in recent years is considered
to be a significant advancement over passive patches due to its ease of
application, cosmetic appeal and reduced skin irritation.
- Transdermal gels
are expected to bolster demand for transdermal technology, especially in
new indications, such as male hypogonadism and female sexual
transdermal technology, which has been in development for more than a
decade, is likely to make its debut as early as 2004, placing the U.S.
transdermal drug delivery market on much firmer footing.
- The total market
for TDD products in the US, major European markets, and Japan was
approximately $2.5 billion in 2001 (this does not include a $1.4 billion
market for plaster/poultice products in Japan).
- 3M transdermal
components are appreciated the world over for high quality, breakthrough
technology, and proprietary patent protection. That’s why 75 percent of
transdermal drug delivery products marketed in the United States today
contain 3M components. These components are used in marketed products
registered in over 60 countries.