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  • Inositol, (of which the most prominent naturally occurring form is myo-inositol, cis-1,2,3,5-trans-4,6-cyclohexanehexol), is a carbocyclic polyol that plays an important role as the structural basis for a number of secondary messengers in eukaryotic cells, including inositol phosphates, phosphatidylinositol (PI) and phosphatidylinositol phosphate (PIP) lipids.
  • It is found in many foods, in particular, in cereals with high bran content, nuts, beans, and fruit, especially cantaloupe melons and oranges. Inositol is not considered a vitamin itself because it can be synthesised by the body.
    Inositol is needed for health at cellular level and a fair concentration is found in the lens of the human eye as well as the heart.
  • Men taking extra inositol reported that their hair loss had improved, with less hair falling out - although this has not been tested under clinical situations
  • Extracts of immature kernels of Zea mays catalysed the synthesis of indol-3- ylacetyl-myo-inositol galactoside from indol-3-ylacetyl-myo-inositol and UDP-galactose.
    The product of the reaction contained radioactivity from UDP-[U-'4C]galactose and was identified as indol-3-ylacetylmyo-inositol galactoside by gas chromatography-mass spectrometry.
  • Indol-3-ylacetyl-myo-inositol galactosyltransferase (indol-3-ylacetylmyo-inositol galactoside synthase) is present in developing kernels of Zea mays.
  • The solution containing IAA-myo-inositol glycosides,used as a standard, was prepared from an acetone/water (7:3, v/v) extract from 300 g of dry kernels. The acetone extract (2600 ml) was evaporated to 20% of its volume and left overnight in a cold-room. After filtration, the filtrate was evaporated to dryness, dissolved in propan-2-ol/water.
  • Myo-inositol (MI), a molecule that is located within astrocytes, is presumed to act as an osmolyte, and its concentration is altered in many brain disorders (1). MI is also involved in the activation of protein C kinase.
  • The enzyme inositol oxygenase (myo-inositol : oxygen oxidoreductase; is a monooxygenase that converts inositol into glucuronic acid in the presence of molecular oxygen.
  • Myo-inositol and several other polyols in cerebrospinal fluid (CSF) and plasma from 10 AD subjects and 10 healthy age-matched controls by using
    a gas chromatographic-mass spectrometric technique.
  • A myo-inositol transport mutant was isolated from UV-mutagenized S. cerevisiae cells using the replica-printing technique.
  • There is a paucity of data on the way (cAMP, inositol), qualitatively or quantitatively, altered in heart failure (HF). These studies were performed separately on animal models, but no study checked cAMP and inositol changes in the same animal model simultaneously.
  • Pig feed is mainly based on cereals where phosphorus (P) is mostly present in inositol hexaphosphate (IP6), which is not readily available to monogastric animals. More available P sources are often added to ensure that pigs’ requirements are fulfilled; this results in high excretion levels of P. The digestibility of P depends on phytase activity and amount of IP6 in feedstuffs.
  • The formation of inositol within the animal body was used for the normal concentration of body inositol and the continued urinary excretion of inositol by rats fed a low inositol diet for prolonged periods.
  • Inositol phosphate-containing molecules play an important role in a broad range of cellular processes. Inositol 5-phosphatases participate in the regulation of these signaling molecules.
  • Inositol is a simple isomer of glucose that is a key metabolic precursor in the phosphatidylinositol cycle.
  • Currently there are 11 active producers of inositol in China, and most of them are distributed in North China.
  • China is a large producing country of inositol in the world, about 80% of whose output was exported to overseas market. Thus overseas demand of inositol has an important impact on Chinese inositol industry.
General Information
  • Inositol information
  • Inositol
  • Inositol Importance
  • About Inositol
  • Structure of Myo-Inositol-1-Phosphate
  • What is Inositol?

Company Profiles

  • Company from China
  • International Company
  • China Company from Anhui
  • Company from New Zealand
  • Company from Japan

Consultants

  • Consultant from UK
  • UK Consultant from Birmingham
  • Consultant from California
  • Consultant from Minnesota
  • Consultant from USA
  • Consultant from China

Process

  • Osmoregulatory changes in myo-inositol transport by renal cells
  • Characterization of Inositol-containing Phosphosphingolipids from Tobacco Leaves
  • Advances in analysis and synthesis of myo-inositol-derivatives through resolution by crystallisation
  • Specificity Determinants in Inositol Polyphosphate Synthesis: Crystal Structure of Inositol 1,3,4-Trisphosphate 5/6-Kinase
  • Biosynthetic Pathways of Inositol and Glycerol Phosphodiesters Used by the Hyperthermophile Archaeoglobus fulgidus in Stress Adaptation
  • Myo-Inositol metabolism in Rhizobium leguminosarum
  • Enzymic synthesis of indol-3-ylacetyl-myo-inositol galactoside
  • Biosynthesis of Inositol in Yeast

Application

  • Choline and Inositol Distribution in Algae and Fungi
  • Inositol ­ Clinical Applications for Exogenous Use
  • Environmental Implications of Inositol Phosphates in Animal Manures
  • Double-Blind, Controlled Trial of Inositol Treatment of Depression
  • The myo-inositol-1-phosphate synthase gene is essential in Trypanosoma brucei
  • Effect of Liquid Feeding, Phosphorus Levels and Phytase Supplementation on Digestibility and Performance
  • Controlled trials of inositol in psychiatry
  • A Diverse Family of Inositol 5-Phosphatases Playing a Role in Growth and Development in Dictyostelium discoideum
  • The Synthesis of Inositol in the immature rat and chick embryo

Technology

  • Correlation of Myo-inositol Levels and Grading of Cerebral Astrocytomas
  • Purification, characterization and functional cloning of inositol oxygenase from Cryptococcus
  • Cerebrospinal fluid and plasma distribution of myoinositol and other polyols in Alzheimer disease
  • Myocardial Concentrations of Inositol and cAMP in Intact Failured Rats
  • A Novel Technique for the Pre-Concentration and Extraction of Inositol Hexakisphosphate from Soil Extracts with Determination by Phosphorus-31 Nuclear Magnetic Resonance
  • Myo-Inositol Transport in Saccharomyces cerevisiae

Patent

  • Microbial Method of Producing Inositol
  • Method of Producing Erythritol
  • Inhibitors of the inositol polyphosphate 5-Phosphatase ship2 molecule
  • Method for Analytical Separation of Inositol Phosphates with Quaternary amine and metal ion complex
  • Inositol Pyrophosphates, and methods of use thereof
  • Inositol Triphosphate Pharmaceutical Compositions
  • Method for Modulating Immune Response with Inositol
Projects
  • Inositol lipid dependent lysosome acidification
  • Quantification of myo-inositol hexakisphosphate in alkaline soil extracts by solution 31P NMR spectroscopy and spectral deconvolution
  • Structural characterization of  di‑myo‑inositol-phosphate synthase (DIPPS) : the first representative of a new class of enzymes
  • Identification and Control of Toxic Substance in Municipal Effluents
  • Inositol Signalling Project
  • Second messengers and mechanisms of ion transport in the cells

Products

  • Inositol - Capsules
  • Choline-Inositol Complex
  • Inositol Crystals by Source Naturals
  • InosoPhate 6TM
  • D-myo-Inositol 1,3,4-trisphosphate
  • Inositol Powder
  • Inositol Pure Soluble Powder
  • SOLGAR Inositol

Material Safety Data Sheet

  • Inositol Assay Medium
  • Cryopro Kit
  • Inositol
  • L-Myo [1,2,3H(N)]
  • Safety data for inositol
  • D-myo-Inositol-1,3,4-triphosphate

Properties

  • Study of the Absorption of Myo-Inositol Hexakisphosphate (InsP6) through the Skin
  • Catalytic properties of inositol trisphosphate kinase: activation by Ca2 and calmodulin
  • Dynamic Properties of an Inositol 1,4,5-Trisphosphate– and Thapsigargin-insensitive Calcium Pool in Mammalian Cell Lines
  • Functional Properties of the Drosophila melanogaster Inositol 1,4,5-Trisphosphate Receptor Mutants
  • Properties of Inositol Polyphosphate 1-Phosphatas
  • Functional properties of Drosophila inositol trisphosphate receptors

Function

  • Absorption of myo-inositol hexakisphosphate (InsP6, phytate) through the skin
  • Effects of inositol, Licl, heparin on the antibody responses to SRBC by normal and immunodeficient XID Mice
  • Effect of Cellular inositol content on ethanol tolerance of saccharomyces cerevisiae in sake brewing
  • Effects of inositol hexaphosphate on proliferation of HT-29 human colon carcinoma cell line
  • Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial
  • Effects of Inositol Starvation on Phospholipid and Glycan Syntheses in Saccharomyces cerevisiae

Market & Report

  • Supply & Demand of Inositol
  • Varying Cost and Free Nicotinic Acid Content in Over-the-Counter Niacin Preparations for Dyslipidemia
  • Inositol-Induced Mania
  • Myo-inositol content in pteridophytes and the isolation and characterization of L-myo-inositol-1-phosphate synthase from Diplopterygium glaucum
  • Dimerization of inositol monophosphatase Mycobacterium tuberculosis SuhB is not constitutive, but induced by binding of the activator Mg2+
  • Disruption of inositol biosynthesis through targeted mutagenesis in Dictyostelium discoideum – Generation and characterisation of inositolauxotrophic mutants
  • Proton MR Spectroscopy of Gliomatosis Cerebri: Case Report of Elevated Myoinositol with Normal Choline Levels

Suppliers & Buyers

  • Suppliers of Inositol
  • Selling leads of Inositol
  • Exporters of Inositol
  • Inositol Trade leads
  • Inositol Manufacturer / Suppliers
  • Inositol Chemical Suppliers
  • Inositol Buyers
  • Inositol Buyers List

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