Pullulan  
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  • Pullulan is a polysaccharide polymer consisting of maltotriose units, also known as a-1,4- ;a-1,6-glucan. Three glucose units in maltotriose are connected by an a-1,4 glycosidic bond, whereas consecutive maltotriose units are connected to each other by an a-1,6 glycosidic bond.
  • Pullulan is produced from starch by the fungus Aureobasidium pullulans. Available as a white powder it is odorless, flavorless, and highly stable. Pullulan is a neutral glucan (like Amylose, Dextran, Cellulose), with a chemical structure somewhat depending on carbon source, producing microorganism (different strains of Aureobasidium pullulans), fermentation conditions.
  • Pullulan is an extremely versatile ingredient providing a technology platform for product innovation. It is an excellent film-former, producing a film which is heat sealable with good oxygen barrier properties and which can also be printed.
  • Pullulan film is sometimes referred to as 'edible packaging'. Importantly colours, flavours and functional ingredients can be entrapped in the film matrix and effectively stabilized. Pullulan can be formed into capsules for use with pharmaceutical and nutraceutical products. Its non-animal origin means there are no 'BSE concerns and it is also suitable for all consumers groups.
  •  Pullulan has about double the adhesive strength of food starch. This property combined with its lack of flavor enables it to be used effectively in typical agglomeration processes.
  • Pullulan can be formed into capsules for use with pharmaceutical and nutraceutical products. Its non-animal origin ensures there are no safely concerns with consumers and it is suitability for all consumers groups. Its excellent oxygen barrier properties ensure that the shelf life of products is optimised.
  • Pullulanases are debranching enzymes that are able to hydrolyze the -1,6 bonds of the linear -glucan pullulan, producing maltotriose as the final product. Pullulanases are divided into two classes based on substrate specificity: (i) type I pullulanases or debranching enzymes, (ii) type II pullulanases or amylopullulanases.
  • The physiological function of pullulan is uncertain. Since Aureobasidium strains cannot break down pullulan significantly to metabolizable sugars, pullulan presumably does not serve as a storage material. It is generally supposed that pullulan and similar polysaccharides serve to protect cells from dessication or help them adhere to environmental substrates.
  • Capsugel's Non-animal Polymer Capsules (NPcaps) are made of pullulan, a water-soluble polysaccharide that is produced from corn syrup by a fermentation process. They contain no genetically modified raw materials. An advantage of pullulan is that it is very stable and well characterised raw material, matching performance characteristics of gelatin.
  • Pullulan got its start with the Listerine breath-freshener pocket packs, which are thin polysaccharide polymer strips that quickly dissolve on the tongue.
  • Pullulan has been used as a food ingredient for over 20 years in Japan. It has Generally Regarded As Safe (GRAS) status in the US for a much wider range of applications and thus higher intakes than the current application.
 General Information
  • Pullulan
  • Pullulan Basic Information
  • History of Pullulan
  • Characteristics of Pullulan
  • Aureobasidium pullulans

Production and Processing

  • Development of an Ideal Starch Sacharification
    Process using Amylolytic Enzymes
  • Fermentation of Starch
  • Pullulan Layer Preparation and Processing
  • Purification of Pullulan
  • Structure of Pullulan
  • Production of Isoamylase
  • Production of Pullulan From Beet Molasses
  • Purification and Properties of a Thermostable Pullulanase
  • Pullulanase Production in Clostridium Thermohydrosulfuricum

Functions & Properties

  • Adhesion of Aureobasidium Pullulans Is Controlled by Uronic Acid
  • Molecular Characterization of Cereal Beta Glucans
  • Characterization of Starch-Debranching
    Enzymes in Pea Embryos
  • Cloning of Pullulanase from Anaerobranca gottschalkii
  • Elution Behavior of Protein and Pullulan
  • Properties of Pullulan

Company Profiles

  • Hayashibara
  • NOF Corporation
  • Advanced Enzyme Technologies Ltd
  • Yushiseihin Co., Ltd
  • Sanqing Biological Products

Consultants

  • David A. Brant
  • Experts in 'pullulan'
  • Stephen P. McCarthy
  • Dr. Ajay Kumar Gupta
  • Devendra Bansal
  • Satyanarayan Bhat
  • Costas G.Biliaderis
  • Kenichi Kuroda
  • Terri A. Camesano

Material Safety Data Sheet

  • Pullulan MSDS
  • Pullulans Data Sheet
  • SkinTight AP
  • Red Pullulan
  • Limit-Dextrizyme
  • Pullulan Kit

Patent 

  • Pullulan Film Compositions
  • Use of Pullulan as a Slowly Digested Carbohydrate
  • Spherical Microparticles Containing Linear Polysaccharides
  • Pullulan and Polyethylene Glycol
  • Pullulan Copolymer
  • Preparation of Pullulanase
  • Molecular Weight And Production of Pullulan
  • United States Patent of Pullulan
Technology & Technique
  • Pullulan Technology
  • Production of x-Amylase by the Ruminal Anaerobic Fungus
  • Pulsed Amperometric Detection (PAD)
  • Hologram Replication using a Dental
    Composite as an Embossing Tool
  • Production of Thermostable Pullulanase
  • Hydrolysis of Starch Using Glucoamylase and Pullulanase
  • Amylopectin Biosynthesis in Rice Endosperm
  • Fermentation Technology
  • Fed-Batch Technique for Pullulan
Applications
  • Uses of Pullulan
  • Edible Films from Pullulan
  • Pharmaceutical Applications of  Pullulan
  • Production of Antimicrobial Films from Aureobasidium Pullulans
  • Alkaline Protease Production by the Marine Yeast Aureobasidium Pullulans
  • Use of Polysaccharides in Medical Applications
  • Biotechnological Applications
  • Oral Delivery of Insulin by Polymer-Coated Liposomes

Products

  • Natrol Gymnema Sylvestre w/Pullulan
  • Pullulan Powder
  • Listerine PocketPaks Cool Mint
  • NPcapsTM Capsules
  • List of Pullulan Products

Market 

  • Global GM Market
  • Pullulan Vegetarian Capsules Market Status
  • Microbial Polysaccharides Based Food Hydrocolloid Additives
  • European Market
  • Echinacea Purpurea in United States
  • Veggie Caps Capture Imagination

Report

  • Biosynthesis of Novel Exopolymers by Aureobasidium pullulans
  • Pullulan Is a Slowly Digested Carbohydrate in Humans
  • Pullulan Nano-Particles Prepared by
    aot/n-Hexane Micellar System.
  • Pullulan PI-20 for use as a New Food Additive
  • FTIR Spectra of Iron Complexes With Dextran, Pullulan and Insulin Oligomers

Project 

  • Developing Bioconversion Processes for High value Carbohydrate Products
  • Advanced Starch Based Materials For Non-Food Applications
  • Value-added Utilization of GEM Normal and High-amylose Line Starch
  • Industrial Sources of Biodegradable Polymers
  • Utilization of Microorganisms and Enzymes For Production of Starch Based Foods

Manufacturers,Suppliers & Buyers

  • Suppliers of Pullulan
  • China Suppliers of Pullulan
  • Manufacturer of Pullulan
  • Exporters of Pullulan
  • Pullulan Distributors
  • Pullulan Derivatives Suppliers
  • Pullulan Buyers

Guidelines

  • Guidelines of Pullulan
  • Pullulanase from Klebsiella Aerogenes
  • Future Direction of Gene Therapy in Tissue Engineering
  • Stability of Biocatalysts
  • Advances in handling Pullulan
  • Red Pullulan FAQ

 

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