- Testosterone is a
steroid hormone from the androgen group. Best known for their
masculinising effects, androgens first kick into action during the
embryonic stages of life. In mammals, testosterone is primarily secreted
in the testes of males and the ovaries of females, although small
amounts are also secreted by the adrenal glands. It is the principal
male sex hormone and an anabolic steroid.
- Testosterone is an
anabolic steroid, which means that not only it possesses a unique
chemical structure but it has the capacity to promote the formation of
bone and muscle in the body. Testosterone is also referred to as an
androgen, which means "male producing". And, certainly, the hormone is
an essential component of maleness.
- Testosterone is a
hormone with quite a personality. Tainted by a history of abuse by
bodybuilders and athletes, testosterone is often pointed to as the cause
of aggression, bulging pectorals, an insatiable sexual appetite and the
almighty hairy chest. Its reputation has been somewhat two-faced.
Testosterone is also well known for its role in the hormonal hotbed that
is male puberty.
- Presently, gas
chromatography– mass spectrometry and high- performance liquid
chromatography (HPLC) are the main methods for the determination of
urinary testosterone and epitestosterone, in which liquid–liquid
extraction (LLE) or solid-phase extraction (SPE) is usually used to
concentrate the analytes prior to analysis.
- The interstitial
cells, which lie between the seminiferous tubules, produce testosterone.
These cells are activated during puberty by two hormones, FSH and
LH,which is called interstitial cell stimulating hormone. A rise in
testosterone production in the young male stimulates his reproductive
organs to develop to their adultsize and causes secondary sex
characteristics to appear.
- The human evolution
is directly influenced by testosterone levels . The mechanism is
differential reproduction within the population. That is, individuals of
higher testosterone will have a reproductive advantage over those of
lower testosterone. Individuals of higher testosterone will be more
aggressive and exhibit increased libido; over time they will reproduce
faster.
- Testosterone is used
in a therapy of different pathological states following by profound
protein decay (chronic infectious diseases, emaciation, surgical
operations, serious injuries, etc), and under derangement of nitrogenous
and phosphorous metabolism. Testosterone medications are prescribed at
sexual functional disorders, vascular disorders, for therapy of tumors
including cancer tumors.
- Testosterone is
responsible for normal growth and development of male sex organs and
maintenance of secondary sex characteristics. It is the primary
androgenic hormone, and its production and secretion are the end product
of a series of hormonal interactions. Gonadotropin- releasing hormone
(GnRH) is secreted by the hypothalamus and controls the pulsatile
secretion of luteinizing hormone (LH) and follicle- stimulating hormone
(FSH) by the anterior pituitary.
- An Institute
commends the Institute of Medicine (IOM) for its thoughtful report
evaluating the pros and cons of conducting clinical trials of
testosterone replacement in older men. It appreciates the effort and
care that went into formulating the report and its recommendations,
including those regarding the design, safety and ethics of conducting
such trials.
- A Report analyzed
DNA samples from a number of established cell lines derived from
Japanese individuals to detect CYP3A4 variations. We have found three
variants in the CYP3A4 coding region and characterized the catalytic
functional diŠerences for testosterone hydroxylation using a mammalian
expression system.
- Testim™, a patented
testosterone replacement therapy gel. Testim, A Companies first
commercial product, will be marketed in the United States by that
company and its professional sales force. Regulatory clearance for
Testim was received only 22 months after initial product development.
The Testim clinical trials were the largest ever conducted in
testosterone replacement therapy. They involved 644 hypogonadal men
treated at more than 70 centers in six countries.
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General
- Testosterone
information
- Testosterone
- Testosterone and
Anabolic Steroids
- The Many Gendered
Hormone
- Testosterone
Implants
- Testosterone Hormone
Information
- Testosterone
Factors
- Testosterone- Access
Reproductive
- The andropause and
testosterone
- Testosterone and
Androgens in Women
Extraction
-
Extraction
of testosterone and epitestosterone in human urine using aqueous
two-phase systems of ionic liquid and salt
-
Extraction
of testosterone and epitestosterone in human urine using
2-propanol–salt–H2O system
- Testosterone
Immunoassay
- A Method of
Extraction of Steroids from Blood
Production
Process
- Testosterone
Production in the Body
- Process of
testosterone production
-
The low
gonadotropin- independent constitutive production of testicular
testosterone is sufficient to maintain spermatogenesis
-
Okadaic
Acid Remarkably Suppresses Testosterone Production in Murine Leydig
Cells
- Determination of
testosterone
-
Improved
Methods for Storage, Transport, Processing, and Analysis
-
Mumps
Virus Decreases Testosterone Production and Gamma Interferon- Induced
Protein 10 Secretion by Human Leydig Cells
-
Development and Validation of a Fecal Testosterone
Biomarker in Mus musculus and Peromyscus maniculatus
-
Female
canaries produce eggs with greater amounts of testosterone when exposed
to preferred male song
Company
Profiles
- Company in
Edinburgh
- Company in
Illinois
- Company in
Ohio
- Company in
USA
- Company in
California
Patent
- Acute Testosterone
Administration
- Method and Apparatus
for Transdermal or Transmucosal Application of Testosterone
- Determination of
testosterone by mass spectrometry
- Transdermal Device
for Administering Testosterone or One of the Derivatives
Thereof
- Intravaginal drug
delivery devices for the administration of testosterone and testosterone
precursors
- Medicament for
Increasing the Testosterone Level
- Methods for
Providing Testosterone and Optionally Estrogen Replacement Therapy to
Women
- Water Soluble Amine
Esters of Testosterone for Intranasal Administration
Technology
- Human Saliva as a
Diagnostic Specimen
-
Novavax
and Esprit Pharma to Co-develop Novel Medicine for Female Sexual Desire
Disorder Esprit Receives North American Marketing
Rights
-
Techniques
in Reproductive Diversity Hormone and DNA Labs
- TransDermal
Technologies
- Expanding Our
Commitment to the Treatment of Urologic Disorders
- Evaluation of
Drinking Water Treatment Technologies for Removal of Endocrine
Disrupting Compounds
Functions
-
Testosterone and cognitive function: current clinical
evidence of a relationship
-
Estradiol
and testosterone concentrations in follicular fluid as criteria to
discriminate between mature and immature oocytes
- Testosterone-Fatty
Acid Esterification
-
A
Steroidogenic Factor-1-Binding Site and Cyclic Adenosine
3',5'-Monophosphate Response Element-Like Element Are Required for
the Activity of the Rat Aromatase Promoter in Rat Leydig Tumor Cell
Lines
- Functions of
testosterone
- Characterization of
testosterone
-
Testosterone modulates mitochondrial aconitase in the
full-length human androgen receptor-transfected PC-3 prostatic carcinoma
cells
-
Effects of
castration on early postnatal development of male accessory sex glands
in the domestic pig
-
Relative
Potency of Testosterone and Dihydrotestosterone in Preventing Atrophy
and Apoptosis in the Prostate of the Castrated Rat
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Consultants
- Consultant on
Steroids
- Consultant in
USA
- Expert in Regulation
of Steroid/Hormones
- Expert in Herbs for
Health
- Nutrition and
Exercise Consulting
Projects
- Testosterone
Depletion and Mitochondrial Damage in Skeletal Muscle
- The Metabolism of
Testosterone by Pig Microsomes and the determination of CYP3A4 Protein
Expression
- The detection of the
misuse of testosterone gel
-
Pharmacokinetics of a new testosterone transdermal
delivery system, TDS ® -testosterone in healthy males
- Endogenous
Testosterone, Testosterone precursors and Metabolites
- Managing Adult Onset
Diabetes with Testosterone
Applications
-
Transdermal testosterone gel: pharmacokinetics,
efficacy of dosing and application site in hypogonadal
men
- Testosterone as a
Mediator of Muscle Tissue Growth
-
Modern
Applications
- Testosterone
Applications
- Testosterone
Replacement Therapy
- Treatment of Male
Hypogonadism With Testosterone
- Usage of
Testosterone
Products
- Depo®-Testosterone
- Intrinsa
- Quantum Testosterone
Complex
- Viraloid®
- Testosterone
Gel
- Human Health
Solutions
- Natural Testosterone
Booster
- Testosterone
Booster
- TESTAdioscin
Market
- The Market for Testosterone Creams and
Gels
- Designing for the
Market
- Auxilium Receives
U.S. FDA Approval to Market Testim™ Testosterone Replacement
Gel
- Preliminary
Screening for the Levels of Testosterone Hormone in the Market Meat in
Tehran
- Lack of testosterone
risk rises with age
Report
- Immunoassays for
Testosterone in Women: Better than a Guess?
- The Relationship
between testosterone and New Venture Creation
- Enhances Sexual
Drive, Heightens Sexual Performance, Increases Energy Levels, Enhances
Mood, Promotes Bone and Muscle Growth
-
Garlic
Supplementation Increases Testicular Testosterone and Decreases Plasma
Corticosterone in Rats Fed a High Protein Diet
- CYP3A4 Gene
Polymorphisms In‰uence Testosterone 6b-hydroxylation
- NIA Statement on IOM
Testosterone Report
- Novel Testosterone
Formulations
Risks
- Brief Exposure to
exogenous Testosterone increase Death Signaling and Adversely affects
Myocardial function After Ischemia
-
Health
Canada warns consumers not to use supplements containing
methyl-1-testosterone due to potential serious health risks
- Testosterone-Containing Hormonal Therapy May Increase
Risk for Breast Cancer
- Testosterone
therapy: The answer for aging men?
- Are Steroids Worth
the Risk?
- Testosterone linked
to lower death risk
Suppliers
- Exporters of
Testosterone
- Testosterone
Suppliers
- Testosterone China
Suppliers
- Testosterone
Manufacturers and Suppliers
Guides
-
A
Reporter's Guide to Testosterone and its Role in Women's
Health
-
Hormones:
A Guide for FTMs
- A Man's Guide to
Testosterone Replacement and Anti Aging Therapies
- Patient's Guide to
Low Testosterone
- How the Brain
Triggers Hormone Production
Order the CD ROM
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