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  • Salicylic acid is the chemical compound with the formula C6H4(OH)CO2H, where the OH group is adjacent to the carboxyl group. This colorless crystalline organic acid is widely used in organic synthesis and functions as a plant hormone. It is probably best known as a compound that is chemically similar but not identical to the active component of aspirin. The name derives from the Latin word for the willow tree (Salix), from whose bark it can be obtained.
  • Salicylic acid crystallizes in small colorless needles which melt at 1 55° C. It is sparingly soluble in cold water, but readily dissolves in hot. It sublimes, but on rapid heating decomposes into carbon dioxide and phenol. Ferric chloride colours its aqueous solution violet. Potassium bichromate and sulphuric acid oxidize it to carbon dioxide and water; and potassium chlorate and hydrochloric acid to chloranil. On boiling with concentrated nitric acid it yields picric acid. When heated with resorcin to 200° C. it gives trioxybenzophenone.
  • Salicylic acid is a white crystalline compound, which can be isolated from the bark of birch trees. Since it is a valuable substance that can be isolated from nature, it is called a useful "natural product". Although it was used historically as an analgesic (pain reliever), today it is commonly used in ointments and plasters for the removal of warts from the skin. Acetylsalicylic acid (an ester derivative) is much more commonly used than salicylic acid itself for pain relief, because the parent compound can be rather irritating to your stomach linings. Acetylsalicylic acid is marketed as aspirin.
  • Methyl salicylate, like salicylic acid, is produced by many plants. It was first isolated from wintergreen leaves, Gaultheria procumbens, and is often called oil of wintergreen.Methyl salicylate is similar to acetylsalicylic acid in that it masks one of the acidic hydrogens in salicylic acid. Methyl salicylate replaces the carboxylic acid hydrogen with a methyl group, -CH3. The result is a relatively unreactive compound that does not liberate salicylic acid efficiently in the body. Consequently, methyl salicylate is not an effective analgesic.
  • Salicylic acid is used to treat acne, warts, dandruff, psoriasis, and similar conditions. In the treatment of acne, it slows the shedding of skin cells in hair follicles, so they do not clog the pores and cause pimples. It also has a keratolytic effect, causing dead cells to slough off. The top layer of skin is removed, and pores unclogged. In treatments for warts, a stronger solution is used. This not only softens the wart so it can be rubbed off, but the irritation stimulates the immune system to attack the human papillomavirus that causes warts.
  • Salicylic acid is used externally for the removal of corns and similar epidermic thickenings. It causes some pain, so that a sedative should be added. A common formula has i 1 parts of the acid, 3 of extract of Indian hemp, and 86 of collodion. There is probably no better remedy for corns. Perspiration of the feet cannot be attacked locally with more success than by a powder consisting of salicylic acid, starch and chalk. These drugs are specific for acute rheumatism.
  • Salicylic acid is used in medicine largely in combination with the alkaline bases, through its action on the neutral salts of these substances, because of their superior solubility. Salicylic acid is specifically a remedy for rheumatism. It is used to best advantage in the acute and sub-acute forms, but will serve an excellent purpose in the chronic forms of whatever character. It is now given in the form of its soluble salts. Relapses are, however, more liable to occur after this agent than after almost any other remedy.
  • According to market analyst, Mintel, the UK functional food market was worth an estimated £1.1bn (€1.6bn) in 2005, having grown 143 per cent since the start of the new millennium.The potential health benefits of herbs and spices have been consistently researched, with studies of the anti-cancer effects of turmeric from curcumin, and capsaicin from red chilli pepper spending significant time in the spotlight recently. The health benefits of salicylic acid are not in question because the compound is the metabolite of acetylsaliclylic acid, more commonly known as aspirin. Recent reports have reported that a daily dose of 75-80 mg of aspirin may halve the risk of colorectal cancer.
 General Information
  • Phenols
  • Salicylic acid
  • p-Salicylic acid
  • Overview of salicylic acid
  • History of aspirin
  • History and Mechanism of action of acetylsalicylic acid


  • Synthesis of Salicylic Acid
  • Salicylic acid synthesis and conjugation
  • Salicylic Acid Synthesis
  • Complete mechanism for synthesis of salicylic acid
  • Synthesis of Salicylic Acid from Oil of Wintergreen
  • Production of Salicylic acid precursors
  • Biosynthesis of Salicylic Acid in Potato Plants
  • Synthesis and Characterization of Methacrylic Derivatives of 5-Amino Salicylic Acid
  • Synthesis of Dysprosium Coordination Polymer of Salicylic Acid
  • Synthesis and evaluation of mutual prodrugs of isoniazid, p-amino salicylic acid
  • Acetylation of salicylic acid
  • Synthesis of Acetylsalicylic Acid
  • Multi-Step Synthesis of Aspirin

Company Profiles

  • Alta Laboratories Ltd.
  • Bansal Trading Company
  • Jiangsu Winpool Industrial Co., Ltd
  • J.M.Loveridge Ltd
  • Paragon Industries
  • Qingdao Union Fine Chemical Co.,Ltd
  • Simco Chemicals Inc.
  • SPR Pharma


  • SRI Consulting
  • John W. Zupancic
  • Jorg J Goronzy
  • Srikumaran (Sri) K. Melethil
  • Joseph P. Noel
  • Mack Thomas Ruffin
  • Sanford M. Bolton

Material Safety Data Sheet

  • Salicylic acid
  • Fisher Scientific-Salicylic acid
  • Salicylic acid, 99+%
  • IPCS-Salicylic acid
  • Salicylic acid ointment
  • Salicylic Acid, Sodium Salt


  • Salicylic acid facial scrub
  • GlyMed Serious Action Salicylic Acid Cleanser
  • Diprosalic lotion
  • Locasalen®
  • Nerisalic®
  • Salicylic acid in skin care products
  • Vipsogal Ointment
  • Clean & clear
  • Salicylic Acid Peel
  • Salicylic acid in health and beauty
  • Acne treatment products
  • Salicylic skin care products
  • List of salicylic acid products


  • Uses of Ingredients: Salicylic acid
  • Salicylic acid used in staphylococcal disease
  • Salicylic acid used in hyperkeratotic skin disorders
  • Effects of Hypnotic, Placebo, and Salicylic Acid treaments on Wart regression
  • Applications of acidium salicylicum
  • Novel Salicylic acid cream treats heel  Hyperkeratosis without Irritation
  • Treatment of Chapped Lips
  • Preparation of aspirin

Functions and Properties

  • Acclimation of tomato plants to salinity stress after a salicylic acid pre-treatment
  • Salicylic acid and systemic acquired resistance to pathogen attack
  • Partial purification and characterization of the DCSA
  • Antipyretic, analgesic, anti-inflammatory and cytotoxic effects of four derivatives of salicylic acid
  • Effect of Salicylic acid on arabidopsis seed germination
  • Influence of  and salicylic acid in the enhancement of capsaicin production
  • Induction by salicylic acid of pathogenesis-related proteins and resistance to alfalfa mosaic virus infection
  • Influence of salicylic acid on the induction of competence for H202 elicitation
  • Distribution kinetics of salicylic acid in the dual perfused rat liver preparation
  • Mechanism of peroxidase actions for salicylic acid
  • Coronatine and salicylic acid
  • Purification and characterization of a soluble salicylic acid-binding protein
  • Role of salicylic acid in regulating cadmium induced oxidative stress
  • Hypersensitive cell death in soybean by salicylic acid
  • Temperature-dependent induction of Salicylic Acid
  • Correlation of Free Salicylic Acid Content
  • Assay for salicylate
  • Composition for solubilizing salicylic acid
  • Salicylic acid esters as perfumes
  • Hydrous salicylic acid solutions
  • Antidiabetic salicylic acid derivatives
  • Process for making pure salicylic acid
  • Silicone gel containing salicylic acid
  • Skin treatment with salicylic acid esters
  • Process for producing salicylic esters
  • Method for the alkylation of salicylic acid


  • Determination of the free salicylic acid concentration in aspirin
  • Salicylic acid degradation from aqueous solutions using pseudomonas fluorescens
  • Induction of chalcone synthase and phenylalanine ammonia-lyase by salicylic acid
  • Inhibition of phenolsulpho transferase  by salicylic acid
  • Salicylic acid nitration by means of nitric acid/acetic acid system
  • Development of PMI-5001, a natural salicylate from Gaultheria procumbens


  • Environmental Impact of Aluminum Sulfate and Salicylic Acid Treated Poultry Litters
  • Potato to variety improvement through gene transfer and virological studies
  • Cryotherapy versus salicylic acid for the treatment of verrucae
  • Effects of low concentrations of salicylic acid on plant growth
  • Quantification of the Acidic Properties of Salicylic Acid
  • Kinetics of Aspirin Hydrolysis in Sodium Carbonate Solution
  • The Ability of Salicylic Acid to Reduce the Damaging Effects of Salt Water Stress
  • Chemistry review projects

Market and Report

  • Rhodia company  market
  • Acetylsalicylic Acid Improves Lipid-Induced Insulin Resistance in Healthy Men
  • Fatal reaction to para-amino-salicylic acid and streptomycin
  • Curry favour with colorectal cancer
  • DOE final report
  • Effectiveness and cost-effectiveness of salicylic acid
  • A Central Role of Salicylic Acid in Plant Disease Resistance
  • Simultaneous determination of aspirin and salicylic acid in limited volume plasma samples by ESI(-)-LC-MS/MS
  • Preliminary Report on the Use of Para-Amino Salicylic Acid in the Treatment of Pulmonary Tuberculosis
  • Quantitative Reflectance Spot Test for the Determination of Acetylsalicylic Acid
  • Study of salicylic acid
  • EMEA summary report
  • Salicylic acid specification sheet
  • Chemical product trends: China report

Manufacturers and Suppliers

  • Heterochem (Dist.) Ltd
  • Online Catalogs of salicylic acid
  • Salicylic acid sell offers
  • Foreign Exporters of salicylic acid
  • Indian Exporters salicylic acid
  • Salicylic Acid Manufacturers
  • Salicylic Acid CAS 69-72-7 suppliers
  • Sell Trade Leads of salicylic acid
  • Salicylic acid sellers
  • Selling leads of salicylic acid


  • Buy offers of salicylic acid
  • Foreign importers of salicylic acid
  • Indian importers of salicylic acid
  • Salicylic acid buyers list

Equipment Suppliers

  • Manufacturers of ceramic heater
  • Controller suppliers
  • Graduated cylinder suppliers
  • Disposable pipettes manufacturers
  • Huayin Jinqiancheng Pharmaceutical Co.,Ltd
  • Reflux condenser suppliers
  • Manufacturers of screw clamps
  • Manufacturers of stirring motor

 Safety and Guides

  • Side effects of Carmex
  • Side effects of salicylic acid
  • Salicylic acid preparations for treating warts
  • Drug information of salicylic acid topical
  • FAQ's about salicylic acid and sodium thiosulphate topical
  • FAQ's about salicylic acid

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