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Information @ a Glance

Contents on the CD Rom

• Coumarin is a chemical compound (benzopyrone); a toxin found in many plants, notably in high concentration in the tonka bean, vanilla grass, woodruff, mullein, and bison grass.
• Coumarin has blood-thinning, anti-fungicidal and anti-tumor activities.
• The biosynthesis of coumarin in plants is via hydroxylation, glycolysis and cyclization of cinnamic acid.
•  Coumarin can be prepared in a laboratory in a Perkin reaction between salicylaldehyde and acetic anhydride.
• The air-dried stem and root barks of Galipea trifololiata contain a third previously unreported coumarin identified as 7-isopentenyloxy.
• coumarin-4-acetic acids 1-3 using method common for peptide synthesis6 .
• Reaction of coumarin-4-acetic acid with -hydroxy succinimide  in the presence of di cyclo hexyl carbo diimide  gave NHS ester, which was coupled with linker moiety to give protected product in yield 57-75% after chromatography.
• Coumarin derivatives (dicumarol, ethyl biscoumacetate, and warfarin) are oral anticoagulants, as are the indandione derivatives.
• Use of any of these agents during pregnancy may result in significant problems for the fetus and newborn.
• Micelles formed by an amphiphilic diblock copolymer composed of PEO and PCMA are electro chemically active in aqueous electrolyte solution, displaying an irreversible oxidation process of coumarin at a potential of about 1.75 V.
• The host–guest complex of C-methyl resorcin arene with coumarin and thiocoumarin has been characterized by single crystal X-ray diffraction technique.
• Coumarin-3-carboxylic acid  and CA anions in free space produce broad emissions centered at 438 nm when excited by 337.1-nm UV light.
• Ultra fast photo induced electron transfer in coumarin 343 sensitized TiO2-colloidal solution.
• New orange fluorescent dyes based on coumarin, which has high fluorescence yield and chemical stability, have been synthesized.
•  It has a sweet scent, readily recognised as the scent of newly-mown hay, and has been used in perfumes.
• It has clinical medical value as the precursor for several anticoagulants, notably warfarin, and is used as a gain medium in some dye lasers.
• Coumarin has been used in the treatment of lymphedema.
• This medication is a blood thinner used to keep blood flowing smoothly and prevent the formation of blood clots.
• Coumarin is also used formedicinal purposes to treat oedemas.

• Coumarin
• What is Coumarin
• Coumarin
• Frequently Asked Questions about coumarin
• Phytochemical
• Coumarin Types Drugs.

• Coumarins
• Effects of Coumarin and Sparteine on Attachment to Cellulose and Cellulolysis by Neocallimastix frontalis
• New Monoterpenoid Coumarins from Clausena anisum-olens
• A Coumarin from Galipea Trifoliata
• Synthesis of Coumarin-functionalized Calix[4]arene and Selective Recognition for L-Tryptophan
• Urinary Metabolites of Coumarin and o-Coumaric Acid
• Synthesis of Novel Coumarin Based Flurocent Probes
• Coumarin The Real Story

• Electrochemically Active Block Copolymer Micelles Containing Coumarin Moieties
• Inhibition of the Symbiotic Fungus of Leaf-Cutting Ants by Coumarins
• Coumarins and Alkaloids from the Stems of Metrodorea Flavida
• Coumarin Derivatives
• Opinion on coumarin
• Coumarin Report

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