L - Selenomethionine
Technology, Products,  Market, Isolation Process, Projects, Suppliers, Company Profiles, Reports 

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  • Selenium is an essential trace mineral for the human body, primarily because it acts as an effective antioxidant preventing harmful cell damage.
  • Selenium is a trace mineral that is essential to good health but required only in small amounts . Selenium is incorporated into proteins to make selenoproteins, which are important antioxidant enzymes.
  • Selenium (Se) is both an essential nutrient as well as a toxic chemical.  This dual effect has been recognized for many naturally occurring chemicals.  Trace amounts are beneficial, while larger amounts are harmful.  Of course the toxicity of selenium depends greatly on the chemical form or species
  • Plant foods are the major dietary sources of selenium in most countries throughout the world. The content of selenium in food depends on the selenium content of the soil where plants are grown or animals are raised
  • Selenium compounds may be used as an arming agent for antibodies, peptides, small molecules, and nucleotides (e.g. aptamers). The selenium technology attached to a targeting agent delivers a lethal payload to tumor cells, pathogenic microbes, or other specific cells. Because of seleniumís unique mode of action, selenium-armed agents have been shown to kill bacteria at 4o C, indicating that there need not be metabolic activity for selenium to be effective.
  • Most recently, scientists have discovered a way to accumulate highly bioavailable forms of selenium in specially cultivated plants of the Crucifer family. Plants in the crucifer family such as broccoli contain particular antioxidants including sulforaphanes, isothiocyanates and indole carbinols that have been linked to improved immune functions and are widely sold as nutritional supplements.
  • The rapid increase in selenium
    price is the result of large
    purchases of selenium by China in second half 2003, depleting refinery inventories. This high demand continues and as spot supply dries up, purchasers are now reportedly trying to locate supply under long term contracts with refiners.
  • Selenium enjoys a wide range of usages that are expanding. Current usage of selenium is as follows: Glass (25.7%), Metallurgy (23.9%), Chemicals (15.2%) , Pigments (10.3%), Electronics (9.1%), Agriculture and Other (15.7%).
  • Consumption is estimated at 2,650 tonnes in 2003 and has been increasing at 1.6% per annum over the period 1990 to 2000. Historically, the growth appears steady; however, the recent market activity of China purchasing all available selenium inventories suggests much larger growth rates in China as its economy expands
    at a very rapid rate .
  • Growing uses of selenium include: Selenium enriched fertilizers are now being used in Finland, New Zealand, China and United States to get selenium into the food chain and as an alternative to selenium addition directly to animal feed. ,  Selenium additives to vitamin supplements,  Selenium treatments are being developed for a number of ailments including dermatology, tendonitis, periodontal disease,
    rheumatoid arthritis, cancer, macular degeneration and cataracts, herpes and lupus inflammation to name a few.,  Selenium is also being used in new thin-screen technology in copper-indium-selenium solar cells
General Information
  • L-Selenomethionine
  • Dietary Supplement Fact Sheet
  • Why L-selenomethionine?
  • Selenium
  • L - Selenomethionine Specifications
  • Selenomethionine Specification Sheet

Products

  • BioCare Selenium
  • Selenium, from, L-Selenomethionine, 200, mcg,
  • Kinoko Ahcc Plus L-Selenomethionine 30 Ct
  • Selenium SeLECT
  • Selenium (L-Selenomethionine) 200mcg 60 tabs from Source Naturals
  • SelenoSource AF

Material Safety Data Sheet

  • L-Selenomethionine
  • DL-Selenomethionine
  • (S)-2-Amino-4-(methylseleno)butanoic Acid
  • L-Selenomethionine Blend
  • SeMet
  • L-Selenomethionine MSDS

Technology

  • Selenomethionine Protein Labeling Using the Escherichia coli Strain KRX
  • Highly efficient selenomethionine labeling of recombinant proteins produced in mammalian cells
  • Shimadzu, Sharp Corporation and Shindengen Electric Develop Amorphous Selenium (a-Se) Film
  • Selenium Technology
  • Brassica as a selenium source
  • Use of Selenium in the Production of Electrolytic Manganese Metal

Patent

  • Antioxidant Medicament
  • Compositions containing allium sativum linn. (garlic) naturally enriched with organic selenium compounds for nutritional supplementation
  • Derivatives of seleno-amino acids
  • Method of using synthetic l-se-methylselenocysteine as a nutriceutical and a method of its synthesis
  • Multi - Antioxidant Medicament
  • Pharmaceutical formulation for treating liver disorders

Isolation Process

  • Relationship Between the Selenium,l Selenomethionine, and Selenocysteine Content of Submerged Cultivated Mycelium of  Lentinula edodes
  • Isolation Process
  • Production of selenomethionine containing protein for MAD
  • Selenomethionine regulation of p53 by a ref1-dependent redox mechanism
  • Speciation of D,L-selenomethionine enantiomers on a b-cyclodextrin  column with fluorimetric and on-line hydride generation inductively coupled plasma mass spectrometric detection

Functions and Properties

  • Selenomethionine Analysis
  • New Generation Organic Selenium (zinc-L-selenomethionine) Increases Muscle Selenium Levels in Chicks
  • Oscillations in Tissue Uptake of 75Se-L-Selenomethionine in Rats and Mice Adapted to Controlled Feeding Schedules
  • Isolation and Properties of Selenomethione - Resistant Mutants of Neurospora Crassa
Projects and Consultants
  • Integrated Systems for Increased  Production Efficiency of Sheep
  • Countermeasures for Space Radiation Induced Myeloid Leukemia 
  • Selenium Nutrition in Humans
  • Specification and bio availability of selenium from processed and tailor-made fishery products
  • Consultant from Pennsylvania
  • Consultant from USA
  • Consultant

Applications

  • New Discoveries Expand Our Knowledge About Selenium's Importance
  • Changes in Serum Proteomic Patterns by Presurgical A-Tocopherol and L-Selenomethionine Supplementation in Prostate Cancer
  • Oral and Tropical L - Selenomethionine Protection from Ultraviolet - Induced Sunburn, Tanning and Skin Cancer
  • Skin Health and Natural Products for Topical and Nutraceutical Skin Care
  • Use of  L-selenomethionine as a label for lymphoid cells

Market and Guidelines

  • Is There a Market for Selenium-Enriched Pork?
  • Market Overview
  • Which Selenium Supplement To Take?
  • Selenium in Drinking-water - Guidelines

Hazards and Regulations

  • Hazards and Protection.
  • Selenomethionine: A Review of Its Nutritional Significance, Metabolism and Toxicity
  • Hazard Summary
  • Toxic Effects
  • Consumer Factsheet

Company Profiles

  • Company from California
  • Company from Belgium
  • Company from Maharashtra
  • Company from Minnesota
  • Company from New Jersey
  • Company from Shanghai
  • Company from America

Suppliers

  • L - Selenomethionine Suppliers
  • Distributor and Supplier
  • Selling Leads
  • Supplier from Connecticut
  • Supplier from Israel
  • Sellers
  • Suppliers

Reports

  • Acatris develops odourless L-selenomethionine
  • Bioaccumulation and Chronic Toxicity of Dietary L-Selenomethionine in Juvenile White Sturgeon
  • The Metabolic Dynamics of Selenium as L-Selenomethionine Upon Ingestion by White Sturgeon
  • New light on human selenium metabolism
  • Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Selenium
  • Selenium Report
 

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